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portada An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions
Type
Physical Book
Publisher
Author
Language
English
Pages
276
Format
Paperback
ISBN13
9780323991339
Edition No.
1

An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions

Mark Ashton Phd Frsc Fhea; Paul W. Groundwater Phd Cchem Frsc; Sophie Stocker Phd Bsc; Adam Todd Phd Frpharms Sfhea (Author) · Academic Press · Paperback

An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions - Mark Ashton Phd Frsc Fhea; Paul W. Groundwater Phd Cchem Frsc; Sophie Stocker Phd Bsc; Adam Todd Phd Frpharms Sfhea

New Book Imported to South Africa
Delivery: 12 Oct - 21 Oct Shipping: 10 to 12 business days.
R 2,497
R 2,497

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Synopsis "An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions"

An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines, and other drugs. Each of the human metabolic processes are covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, this book is for students and researchers needing a reference for interdisciplinary research in drug interactions. Metabolism is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects.

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