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portada Aptamers
Type
Physical Book
Publisher
Author
Language
English
Pages
300
Format
Paperback
Dimensions
24.4 x 17.0 x 2.1 cm
Weight
0.64 kg.
ISBN13
9783038970590
Categories

Aptamers

Tanner, Julian Alexander ; Kin, Andrew Brian ; Cheung, Yee-Wai (Author) · Mdpi AG · Paperback

Aptamers - Tanner, Julian Alexander ; Kin, Andrew Brian ; Cheung, Yee-Wai

New Book Imported to South Africa
Delivery: 13 Aug - 21 Aug Shipping: 4 to 5 business days.
R 1,304
R 1,304

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Synopsis "Aptamers "

Aptamers are in vitro selected oligonucleotides capable of specific, high-affinity binding to a wide variety of target molecules. These features enable their application in diagnostics, therapeutics, targeted delivery, fluorescence imaging, and biosensing. Aptamers are isolated via the systematic evolution of ligands by exponential enrichment (SELEX), an iterative cycle of selection and amplification steps that enriches a randomly synthesised oligonucleotide library to a pool of specific, high-affinity aptamers. Since the inception of aptamers in 1990, the methods by which aptamers are selected have been improved, yielding a robust system capable of producing aptamers rapidly and at low cost. Recently, there has been an explosion in the field of aptamers including innovations in enhanced selection strategies, bioinformatics approaches, riboswitches, unnatural base pairs, nucleic acid nanostructures, and DNAzymes. This book combines excellent reviews with primary research articles to provide multidisciplinary perspectives on the frontiers of aptamer science in 2018.

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