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portada Comparison of Extraction Methods for an Anticancer Drug, Vinblastine
Type
Physical Book
Publisher
Author
Language
English
Pages
64
Format
Paperback
ISBN13
9783659716850

Comparison of Extraction Methods for an Anticancer Drug, Vinblastine

Javad Sumera; Sarwar Sumera; Naz Shagufta (Author) · Lap Lambert Academic Publishing · Paperback

Comparison of Extraction Methods for an Anticancer Drug, Vinblastine - Javad Sumera; Sarwar Sumera; Naz Shagufta

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Delivery: 21 Oct - 29 Oct Shipping: 13 to 14 business days.
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Synopsis "Comparison of Extraction Methods for an Anticancer Drug, Vinblastine"

In the present study a comparison was made between different extractions methods for anticancer drug Vinblastine from Catharanthus roseus. Extraction was carried out by using two different methods i.e., Microwave Assisted Extraction (MAE) and Soxhlet Extraction using ethanol and a few drops of conc. HCl as an extracting solvent. Estimation of Vinblastine was done by using High Performance Liquid Chromatography (HPLC) by using acetonitrile as mobile phase. Microwave assisted extraction was proved to be a better approach for rapid and efficient extraction of Vinblastine from plant material. It was found that Microwave assisted extraction gave the maximum amount of extract of Catharanthus roseus that is 0.43 g while using lesser time of extraction (30 seconds) with a very little amount of solvent used (10 mL/g) as compared to Soxhlet extraction (23.01 g in 10 hours).

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