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portada Dissolution Improvement of Fenofibrate by Fusion & Kneading Technique
Type
Physical Book
Author
Publisher
Language
English
Pages
112
Format
Paperback
Dimensions
22.9 x 15.2 x 0.7 cm
Weight
0.18 kg.
ISBN13
9786139864386
Categories

Dissolution Improvement of Fenofibrate by Fusion & Kneading Technique

MD Zakaria Faruki (Author) · Elizabeth Razzaque (Author) · A. K. M. Mofasser Hossain (Author) · LAP Lambert Academic Publishing · Paperback

Dissolution Improvement of Fenofibrate by Fusion & Kneading Technique - Faruki, MD Zakaria ; Razzaque, Elizabeth ; Hossain, A. K. M. Mofasser

New Book Imported to South Africa
Delivery: 22 Jul - 14 Aug Shipping: 12 to 13 business days.
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R 1,030

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Synopsis "Dissolution Improvement of Fenofibrate by Fusion & Kneading Technique"

With the progression of time it has become the crucial need to invent more comprehensive drug to meet the challenge of overcoming critical and newly known diseases. Most of the newly discovered chemical entities, in spite of high therapeutic activity, have low aqueous solubility and poor bioavailability, leading to poor absorption in the gastrointestinal tracts. But in case of these newly invented drug molecules as well as existing drug products, oral bioavailability and solubility are still obstacles in formulation development. Therefore, the objective of the study was to develop solid dispersion by different methods especially Fusion & Kneading technique and investigate them for in vitro performance for enhancing dissolution and bioavailability respectively, because solubility and dissolution rate are the key determinants of oral bioavailability.

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