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portada Drug-drug interaction of antiarrhythmic drugs with oral hypoglycemics
Type
Physical Book
Author
Publisher
Language
English
Pages
264
Format
Paperback
Dimensions
22.9x15.2x1.5 cm
Weight
0.39 kg.
ISBN13
9786207458936
Categories

Drug-drug interaction of antiarrhythmic drugs with oral hypoglycemics

Jyotsna P. Khedkar (Author) · Prashant S. Salunke (Author) · LAP Lambert Academic Publishing · Paperback

Drug-drug interaction of antiarrhythmic drugs with oral hypoglycemics - Khedkar, Jyotsna P. ; Salunke, Prashant S.

New Book Imported to South Africa
Delivery: 16 Oct - 26 Oct Shipping: 13 to 14 business days.
R 1,747
R 1,747

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Synopsis "Drug-drug interaction of antiarrhythmic drugs with oral hypoglycemics"

Drug interactions can have a significant clinical impact on patients and can be extremely dangerous or even harmful. A common antiarrhythmic medication for treating cardiac arrhythmia is amiodarone. Amiodarone has a potent inhibitory effect on the CYP2C9 and CYP3A4 isoenzymes. Similar to this, the isoenzymes CYP2C9 and CYP3A4 metabolise anti-diabetic medications such rosiglitazone, pioglitazone, repaglinide, and nateglinide. CYP3A4breaks down sitagliptin and teneligliptin. Glibenclamide and glimepiride are bothmetabolised by CYP2C9 and CYP3A4, respectively. A pharmacological interaction between amiodarone and antidiabetic drugs is therefore entirely possible. Therefore, the goal of the current investigation is to comprehend any potential interactions between amiodarone and antidiabetic drugs. Study carried out at DCS's ARA college of Pharmacy, Dhule Maharashtra for fulfillment of Doctor of Philosophy of Lincoln University College Malaysia.

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