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portada Enantiomeric separation of Valganciclovir by HPLC and LC/MS methods
Type
Physical Book
Author
Publisher
Language
English
Pages
84
Format
Paperback
Dimensions
22.9 x 15.2 x 0.5 cm
Weight
0.14 kg.
ISBN13
9786202554305
Categories

Enantiomeric separation of Valganciclovir by HPLC and LC/MS methods

Byran Gowramma (Author) · Subramania Nainar Meyyanathan (Author) · Rajagopal Kalirajan (Author) · LAP Lambert Academic Publishing · Paperback

Enantiomeric separation of Valganciclovir by HPLC and LC/MS methods - Gowramma, Byran ; Meyyanathan, Subramania Nainar ; Kalirajan, Rajagopal

New Book Imported to South Africa
Delivery: 03 Sep - 11 Sep Shipping: 13 to 14 business days.
R 817
R 817

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Synopsis "Enantiomeric separation of Valganciclovir by HPLC and LC/MS methods"

Chiral separations occupy an important sector of HPLC-type analyses since many bioorganic molecules, as well as many pharmaceutical drugs, are chiral.However, the selection of a column in chiral separation and the development of a successful HPLC procedure remain a rather difficult subject. The differences in the interaction forces between enantiomers are typically small, and specific phases are more suitable than others for a specific separation.he selection of a chiral column for developing a separation is typically based on manufacturer recommendations. The selection of a chiral column for developing a separation is typically based on manufacturer recommendations. Among the different chiral stationary phases (CSPs) used in chiral HPLC, the polysaccharide CSPs have proved to be very useful and might be recommended as first-choice columns when one wants to develop chiral separations. These CSPs know many applications, both in normal-phase and reversed-phase mode. The chiral selectors of these CSPs have a broad enantiorecognition range (80% of marketed drugs), which makes them excellent candidates for developing both screening strategies and individually optimized separations.

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