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portada Improved solubilization of silymarin via incorporation in a nanosystem
Type
Physical Book
Author
Publisher
Language
English
Pages
52
Format
Paperback
Dimensions
22.9x15.2x0.3 cm
Weight
0.09 kg.
ISBN13
9786138835608
Categories

Improved solubilization of silymarin via incorporation in a nanosystem

Amira Mohsen (Author) · Scholars' Press · Paperback

Improved solubilization of silymarin via incorporation in a nanosystem - Mohsen, Amira

New Book Imported to South Africa
Delivery: 23 Nov - 01 Dec Shipping: 14 to 15 business days.
R 906
R 906

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Synopsis "Improved solubilization of silymarin via incorporation in a nanosystem"

Silymarin is a complex mixture extracted from the seeds and fruits of Silybum marianum. It has been widely used for the treatment of liver disorders. It was also found to be effective against certain cancers, such as breast, prostate, and skin cancers. Silymarin absorption rate levels range between 20 and 50%. This poor bioavailability may be due to poor solubility, degradation by gastric fluid or its poor enteral absorption. Considering these limitations, new drug delivery systems were developed in order to increase its solubility and oral absorption. Nanoemulsion offers numerous advantages over other drug delivery systems such as higher solubilization ability, rapid onset of action, and extended shelf life. The present study emphasizes the formulation and evaluation of silymarin loaded nanoemulsion aiming at enhancing its solubilization and oral bioavailability.

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