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portada infection, immune homeostasis and immune privilege
Type
Physical Book
Illustrated by
Publisher
Author
Year
2012
Language
English
Pages
156
Format
Hardcover
Dimensions
23.4x16x1.8 cm
Weight
0.36 kg.
ISBN
303480444x
ISBN13
9783034804448
Categories

infection, immune homeostasis and immune privilege

Joan Stein-Streilein (Illustrated by) · Springer · Hardcover

infection, immune homeostasis and immune privilege - Stein-Streilein, Joan

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Synopsis "infection, immune homeostasis and immune privilege"

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated "immune-privileged sites" by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

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