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portada Male-Mediated Developmental Toxicity
Type
Physical Book
Publisher
Author
Language
English
Pages
278
Format
Hardcover
ISBN13
9781839167195
Edition No.
0002
Categories

Male-Mediated Developmental Toxicity

Anderson, Diana ; Habas, Khaled (Author) · Royal Society of Chemistry · Hardcover

Male-Mediated Developmental Toxicity - Anderson, Diana ; Habas, Khaled

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Synopsis "Male-Mediated Developmental Toxicity"

Germ cells have a unique and critical role as the conduit for hereditary information. The issue of male germline mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile in recent years. Understanding the mechanisms by which the germline is induced and maintained is one of the effective ways to treat infertility and cancer. Male-mediated Developmental Toxicity discusses these issues and provides analysis of the fundamental mechanisms of mutations covering both clinical and experimental aspects. It helps clarify the data explaining how genotoxicity involves multiple modes of action and highlights novel models and assays being used to assess germ cell genotoxicity. With a clear focus on the various mechanisms that could impact human health, this book is for postgraduate students and researchers in reproductive and developmental toxicology as well as those with an interest in the fields of genetically inherited diseases, developmental biology and, potentially, those with a more clinical background.

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