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portada Membrane Structure and Mechanisms of Biological Energy Transduction
Type
Physical Book
Publisher
Author
Language
English
Pages
602
Format
Paperback
Dimensions
22.9 x 15.2 x 3.2 cm
Weight
0.82 kg.
ISBN13
9781468420180
Categories

Membrane Structure and Mechanisms of Biological Energy Transduction

Avery, J. (Author) · Springer · Paperback

Membrane Structure and Mechanisms of Biological Energy Transduction - Avery, J.

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Synopsis "Membrane Structure and Mechanisms of Biological Energy Transduction"

The problem of electron transfer phosphorylation was first formu- lated in 1939 by Belitser and Tsibakova I who introduced the "P: 0" criterion and showed that this ratio is more than 1. The authors noted that such a high value of the phosphorylation coefficient suggests a fundamental difference in the mechanisms of A TP formation coupled with respiration, and glycolysis, since in the latter case, the amount of the ATP synthesized is equal to that of the substrate utilized. A lot of hypothetical schemes were put forward to explain the nature of coupling between electron transfer and phosphorylation, but none of them solved the problem. Only quite recently, one hypo- thetical scheme of energy coupling, viz. Mitchell's chemiosmotic concept, 2.3 was supported by experimental data which allow us to prefer it to alternative possibilities. In this paper, I shall try to substantiate the statement that oxidation and phosphorylation can be coupled via a membrane potential as was postulated by Mitchell.

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