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portada modelling of gpcrs
Type
Physical Book
Author
Publisher
Language
English
Format
Hardcover
Dimensions
24.1 x 16.0 x 1.7 cm
Weight
0.59 kg.
ISBN
9400745958
ISBN13
9789400745957
Categories

modelling of gpcrs

Andrea Strasser (Author) · Hans-Joachim Wittmann (Author) · Springer · Hardcover

modelling of gpcrs - Strasser, Andrea ; Wittmann, Hans-Joachim

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Synopsis "modelling of gpcrs"

G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell. Besides that a large number of drugs, available on market, address GPCRs. For an efficient and improved development of appropriate drugs, molecular modelling of GPCRs is - in order to understand the ligand-receptor interactions and functionality of GPCRs on molecular level - an important tool. The book "Modelling of GPCRs - a practical handbook" is focussed onto a practical introduction into molecular modelling of GPCRs. This book is very useful for beginners in GPCR modelling, but also addresses the advanced GPCR modeller: On the one hand, the book introduces principles of GPCR modelling, including extensive examples. On the other hand, detailed outlooks onto advanced GPCR modelling techniques are presented. Furthermore, the book includes important data, like information about crystal structures in a summarized manner or amino acid sequences, which are essential for GPCR modelling in general. Due to an increase in efficacy and data handling most modellers use LINUX as operating system. To address this, a summary of most important LINUX commands with examples is presented within the book.

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