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portada Neurologic Channelopathies (Volume 203) (Handbook of Clinical Neurology, Volume 203)
Type
Physical Book
Publisher
Author
Language
English
Pages
292
Format
Hardcover
ISBN13
9780323908207
Edition No.
1

Neurologic Channelopathies (Volume 203) (Handbook of Clinical Neurology, Volume 203)

Hanna Michael G. (Author) · Elsevier · Hardcover

Neurologic Channelopathies (Volume 203) (Handbook of Clinical Neurology, Volume 203) - Hanna Michael G.

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Synopsis "Neurologic Channelopathies (Volume 203) (Handbook of Clinical Neurology, Volume 203)"

Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management. In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological, and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.

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