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portada Nf-Kb, a Network Hub Controlling Immunity, Inflammation, and Cancer
Type
Physical Book
Language
English
Pages
272
Format
Paperback
Dimensions
25.1 x 17.8 x 1.5 cm
Weight
0.59 kg.
ISBN
1936113554
ISBN13
9781936113552
Categories

Nf-Kb, a Network Hub Controlling Immunity, Inflammation, and Cancer

Michael Karin (Author) · Cold Spring Harbor Laboratory Press · Paperback

Nf-Kb, a Network Hub Controlling Immunity, Inflammation, and Cancer - Karin, Michael

New Book Imported to South Africa
Delivery: 17 Jul - 14 Aug Shipping: 12 to 16 business days.
R 892
R 892

Synopsis "Nf-Kb, a Network Hub Controlling Immunity, Inflammation, and Cancer"

NF-kB is a critical signaling molecule in the immune system that regulates cell survival and cell death, lymphocyte responses, and inflammation. Acting as a transcription factor that can receive several inputs, it coordinates distinct gene expression programs in response to a wide variety of stimuli. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structure of NF-kB, its DNA-binding activity and specificity, the role of the inhibitor I-kB, and canonical and alternative mechanisms of NF-kB activation. The contributors examine the physiological role of NF-kB in immune cells, as well as its functions in other tissues, such as the nervous system. They also discuss work indicating that NF-kB represents a critical link between inflammation and cancer. Including clinical perspectives on the use of NF-kB inhibitors in cancer therapy and a historical introduction by David Baltimore, in whose lab NF-kB was discovered, this volume is a vital reference for cell and molecular biologists, immunologists, and pathologists interested in regulation of cell function.

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All books in our catalog are Original.
The book is written in English.
The binding of this edition is Paperback.

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