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portada Protein Kinase-Mediated Decisions Between Life and Death
Type
Physical Book
Publisher
Author
Language
English
Pages
415
Format
Hardcover
Dimensions
25.4x17.8x2.4 cm
Weight
0.95 kg.
ISBN13
9783030498436
Categories

Protein Kinase-Mediated Decisions Between Life and Death

Engin, Ayse Basak ; Engin, Atilla (Author) · Springer · Hardcover

Protein Kinase-Mediated Decisions Between Life and Death - Engin, Ayse Basak ; Engin, Atilla

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Synopsis "Protein Kinase-Mediated Decisions Between Life and Death"

Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on "Protein Kinases" related pathways that threaten human health and life. As "Protein Kinases" are related to many health problems, clinicians, basic science researchers and students need this information.Chapter "Signal Transduction in Immune Cells and Protein Kinases" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

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