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portada signaling pathways in cancer pathogenesis and therapy
Type
Physical Book
Illustrated by
Publisher
Author
Language
English
Pages
148
Format
Hardcover
Dimensions
23.1 x 15.7 x 1.5 cm
Weight
0.36 kg.
ISBN
1461412153
ISBN13
9781461412151
Categories

signaling pathways in cancer pathogenesis and therapy

David a. Frank (Illustrated by) · Springer · Hardcover

signaling pathways in cancer pathogenesis and therapy - Frank, David a.

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Synopsis "signaling pathways in cancer pathogenesis and therapy"

In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.

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