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portada Studies on the Synthesis & Characterization of Mangiferin Analogues
Type
Physical Book
Author
Publisher
Language
English
Pages
108
Format
Paperback
Dimensions
22.9x15.2x0.7 cm
Weight
0.17 kg.
ISBN13
9786203409840
Categories

Studies on the Synthesis & Characterization of Mangiferin Analogues

Shashi Kant Singh (Author) · LAP Lambert Academic Publishing · Paperback

Studies on the Synthesis & Characterization of Mangiferin Analogues - Singh, Shashi Kant

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Synopsis "Studies on the Synthesis & Characterization of Mangiferin Analogues"

The naturally occurring xanthone glycoside mangiferin has been isolated by column chromatography from the ethanolic extract of stem bark of Mangifera indica. Mangiferin was further converted to Mangiferin-octa-Acetate, Mangiferin-tetra-benzoate, 5-(N-phenylamino methyleno) mangiferin, 5-(N-p-chlorophenylamino methyleno) mangiferin, 5-(N-2-methyl phenylamino methyleno) mangiferin, 5-(N-p-Methoxy phenylamino methyleno) mangiferin, 5-(N, N-Diphenylamino methyleno) mangiferin, 5-(N--Napthylamino methyleno)-mangiferin, 5-(N-4-methyl phenylamino methyleno) mangiferin, 5-(N-m-Nitrophenylamino methyleno) mangiferin, 5-(N-p-flurophenylamino methyleno) mangiferin, Octa-o-methyl mangiferin, Mangiferin-9- Oxime. Mangiferin and its analogues were characterized by mp, Rf, UV, IR, and NMR spectral analyses. These compounds were screened for antimicrobial activity. Among the compound tested, only MPAMM-4, a mangiferin derivative was found to be more effective than other compounds against both bacteria (Escherichia coli) and fungus (Aspergillus niger).

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