Name: Synthesis and characterization of drug carrier based on polysaccharides
Price: 996.00 ZAR
Availability: InStock
Author: Patel, Prof (Dr ). Nirmal K. ; Patel, Savan H.
ISBN: 9783346788269

portada Synthesis and characterization of drug carrier based on polysaccharides

Synthesis and characterization of drug carrier based on polysaccharides

Type

Physical Book

Author

Prof (Dr ). Nirmal K. Patel

Savan H. Patel

Publisher

Grin Verlag

Language

English

Pages

254

Format

Paperback

Dimensions

21.0 x 14.8 x 1.5 cm

Weight

0.34 kg.

ISBN13

9783346788269

Synopsis "Synthesis and characterization of drug carrier based on polysaccharides"

Doctoral Thesis / Dissertation from the year 2022 in the subject Chemistry - Other, language: English, abstract: The title of this thesis "Synthesis and Characterization of Drug Carrier Based on Polysaccharides" clearly reflects the objective, which is an approach towards preparation of excipients, defined as 'the substance used as a medium for giving a medicament', that is to say with simply the functions of an inert support of the active principle or principles. Okra gum, obtained from the fruits of Hibiscus esculents, is a polysaccharide consisting of D-galactose, L-rhamnose and L-galacturonic acid. It is used as a binder. In studies okra gum has been evaluated as a binder in paracetamol tablet formulations. These formulations containing okra gum as a binder showed a faster onset and higher amount of plastic deformation than those containing gelatin. The crushing strength and disintegration times of the tablets increased with higher binder concentration, while their friability decreased. Although gelatin produced four tablets with higher crushing strength, okra gum produced tablets with longer disintegration times than those containing gelatin. It was finally concluded from the results that okra gum may be a useful hydrophilic matrixing agent in sustained drug delivery system. Various strategies were developed in order to overcome these issues, offering the opportunity to tailor the physical and chemical properties of okra gum thus yielding materials that may find a wide range of applications. Extraction and purification of okra gum was carried out from okra pods. Followed by carboxymethylated and phosphorylation of extracted okra gum, which was carried out along with optimization of reaction parameter of the primary derivatives that is carboxymethylated okra gum and hydroxyl propyl okra phosphate, followed by drug carriers preparation. By the second modification carboxymethylated okra gum and hydroxyl propyl okra phosphate were carried out by cross link

Customers reviews

Have you read this book? Login to add your review.

More customer reviews

0% (0)
0% (0)
0% (0)
0% (0)
0% (0)

Questions and Answers about the Book

Do you have a question about the book? Login to be able to add your own question.

Opinions about Bookdelivery

More customer reviews

Synthesis and characterization of drug carrier based on polysaccharides - Patel, Prof (Dr ). Nirmal K. ; Patel, Savan H.

Synopsis "Synthesis and characterization of drug carrier based on polysaccharides"

Customers reviews

Frequently Asked Questions about the Book

Is the book original?

In what language is the book written?

What is the format of this book?

Questions and Answers about the Book

Opinions about Bookdelivery