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portada The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness
Type
Physical Book
Author
Publisher
Topic
Biostatistics
Year
2014
Language
English
Pages
272
Format
Hardcover
Dimensions
23.6 x 16.0 x 2.3 cm
Weight
0.57 kg.
ISBN
1118645855
ISBN13
9781118645857
Edition No.
1
Categories

The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness

Gilberto Levy (Author) · Bruce Levin (Author) · Wiley · Hardcover

The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness - Levy, Gilberto ; Levin, Bruce

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R 2,188
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Synopsis "The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness"

A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion--with consequential biomedical and public health relevance--of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.

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